Integration of whole genome sequencing and transcriptomics reveals a complex picture of the reestablishment of insecticide resistance in the major malaria vector Anopheles coluzzii전체 게놈 시퀀싱 및 전 사체의 통합은 주요 말라리아 벡터 Anopheles coluzzii에서 살충제 저항성의 재건에 대한 복잡한 그림을 보여줍니다.Research Article Published on 2021-12-232022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] alteration Anophele approach block change changes in colony complex complexity determine diagnostic Diagnostic markers elevated expression of gene Genetic genetic background Genome genomic genomic change increase in increased respiratory rate increasingly insecticide integration inversion Laboratory malaria malaria control malaria vector marker mechanism metabolism microbial Microbiome original oxidative phosphorylation pathway phenotype Population Pyrethroids respiratory rate reveal RNAseq Sequencing subject subset susceptible Transcriptome transcriptomic transcriptomics translated whole genome Whole genome sequencing [DOI] 10.1371/journal.pgen.1009970 PMC 바로가기 [Article Type] Research Article
Permethrin resistance in Aedes aegypti : Genomic variants that confer knockdown resistance, recovery, and deathAedes Aegypti의 퍼메 트린 저항 : 녹다운 저항, 회복 및 사망을 부여하는 게놈 변이체Research Article Published on 2021-06-172022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] Aede Amino acid amino acid substitution amino acid substitutions association calcium calcium channel Chikungunya comparison Concentration cuticle dead death Dengue dependent on detoxification detoxification enzymes develop directional disease disease control disease outbreaks effective Frequency functional Genes genetic background Genome genomic genomic variant genomic variants heterogeneous population identify IMPROVE individual information insecticide insecticides knockdown knockdown resistance lead list marker mechanism metabolism moderate Mosquito Mutation occur Outbreaks penetration performed Permethrin phenotype phenotypic polymorphism Population populations Prevent proportion protein coding genes Proteins provide public health pyrethroid Pyrethroids reduce Region resistance mechanism resistance mechanisms response sequenced single-nucleotide Single-nucleotide polymorphisms SNPs sodium sodium channel suppress suppression survival tested transmitted Treatment Vaccine variant vector control viral disease Viral diseases voltage voltage-gated sodium channel Zika Zika viruses [DOI] 10.1371/journal.pgen.1009606 PMC 바로가기 [Article Type] Research Article
Culling Dogs for Zoonotic Visceral Leishmaniasis Control: The Wind of ChangeReview Published on 2019-02-012023-06-22 Journal: Trends in parasitology [Category] 조류인플루엔자, [키워드] Canine leishmaniosis Control culling dogs Leishmania infantum Pyrethroids zoonosis. [DOI] 10.1016/j.pt.2018.11.005 PMC 바로가기 [Article Type] Review
Field-Caught Permethrin-Resistant Anopheles gambiae Overexpress CYP6P3, a P450 That Metabolises Pyrethroids현장에서 포착된 퍼메트린 내성 Anopheles gambiae CYP6P3, 피레스로이드를 대사하는 P450 과발현Research Article Published on 2008-11-282022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] A. gambiae adaptive adaptive mechanism adaptive mechanisms Alpha alpha-cyano Anopheles gambiae anopheline mosquitoes Author bioassays compounds Critical CYP6P3 cytochrome P450 detect disease spread Efficacy ENCODE enzyme Enzymes Evolution facilitate found Frequency Gene Gene Expression Genetic Health health problem identify individual insect insecticide insecticides Insects involved lead low frequencies malaria malaria vector malaria vector control mechanism Messenger RNA Metabolic resistance metabolise Molecular assay molecular mechanism molecular mechanisms MONITOR natural selection overexpressed P450 pesticide pesticides phenotyped populations public health pyrethroid Pyrethroids receiving recessive allele reducing resistance significantly sub-Saharan Africa Survivors sustainability trait transcript level translated Transmission undergo [DOI] 10.1371/journal.pgen.1000286 PMC 바로가기 [Article Type] Research Article